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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: Sho-saiko-to, a traditional herbal medicine, regulates gene expression and biological function by way of microRNAs in primary mouse hepatocytes

Figure 1

A schematic illustration of the analysis strategy. Temporally expressed genes from the gene expression microarray dataset have been integrated with a microRNA expression microarray dataset in which putative target gene information of microRNA was obtained from the MicroRNA Database (miRDB version 4.0; http://mirdb.org). Pairs of gene and microRNA showing statistically significant negative correlations are selected by using a random sampling-based permutation method. The resultant targets or non-targets of the microRNAs are subjected to pathway or promoter analysis.

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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