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Table 1 Histopathological analysis of tubular necrosis, PTC congestion and interstitial edema in the five experimental groups

From: Antioxidant effect of Phyllanthus emblica extract prevents contrast-induced acute kidney injury

 

Control (n = 6)

CM (n = 6)

CM PE 125 mg (n = 6)

CM PE 250 mg (n = 6)

CM PE 500 mg (n = 6)

Tubular necrosis and proteinaceous casts

0.1 ± 0.3

2.1 ± 0.5#

1.6 ± 0.5

1.3 ± 0.5*

0.7 ± 0.5*

PTC congestion

0.3 ± 0.5

2.3 ± 0.5#

2.1 ± 0.5

1.8 ± 0.4*

0.8 ± 0.4*

Interstitial edema and infiltration

0.2 ± 0.4

2.4 ± 0.5#

2.1 ± 0.5

1.8 ± 0.4*

0.8 ± 0.4*

  1. The score of histopathological changes, such as scores of tubular necrosis and proteinaceous cast, PTC congestion, interstitial edema and infiltration, are presented as means ± SD.
  2. # P < 0.05; compared to control.
  3. * P < 0.05; compared to CM.
  4. CM: contrast media; PTC: peritubular capillaries.