Effect of electroacupuncture stimulation at Zusanli acupoint (ST36) on gastric motility: possible through PKC and MAPK signal transduction pathways

Table 4 Gene change comparing EA inhibitory group with non-acupoint group

Signal pathway	Gene	Sites	EA/Non-acupoint (Fold change)	EA/Non-acupoint (Fold up- or down-regulation)
MAPK	MAPK6 (ERK3)	D02	0.18	-5.67
MAPK	MAPK10 (JNK3)	D07	0.42	-2.40
MAPK	MAPK11 (p38bMAPK)	D08	0.39	-2.58
MAPK	MAPK13	D10	0.28	-3.58
MAPK	MAPK3 (ERK1)	G11	0.26	-3.83
MAPK	MAPK14 (p38MAPK)	D11	0.47	-2.13
PKC	FGF2	F07	0.37	-2.67
PKC	IL1R1	F08	0.30	-3.31
PKC	IL1R2	F09	0.36	-2.81
PKC	MMP9	F11	0.22	-4.48
PKC	MYC	F12	0.39	-2.59
PKC	PRKCA	G01	0.23	-4.27
PKC	PTGS2	G02	0.19	-5.36
PKC	COL1A1	F05	4.81	4.81

Fold-change (2^-ΔΔCt) is the normalized gene expression (2^-ΔCt) in the test sample divided by the normalized gene expression (2^-ΔCt) in the control sample. Fold-regulation represents the fold-change results in a biologically meaningful way. Fold-change values greater than one indicate a positive- or up-regulation, and the fold-regulation is equal to the fold-change. Fold-change values less than one indicate a negative or down-regulation, and the fold-regulation is the negative inverse of the fold-change.

ISSN: 2662-7671