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Table 2 Therapeutic effect of acupuncture on premenstrual syndrome

From: Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder: systematic review

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Acupuncture points

Frequency

Sample

2 cycles of pre-rating

Baseline

Outcome (end-of-Tx score)

Control

Adverse

P-value

Tx sessions

Size

(no of CG)

Events

1

SP6 CV6 + LR3, LR2, SP10, LI4 or + ST368

13 @ L/FP

10

Not reported

MSSL

7.56 ± 2.36

SI 5

None reported

P < 0.05

2/wk, 8 wks (2 cycles)

16.78 ± 4.30

ST 40

(10)

2

DU20 LI4 H3 REN3,4,6 PE6 GB34 UB23, Auriculoacu-point Shenmen9

2 ~ 4 @ LP

18

Not reported

Diagnosed as PMS

77.8% reduction

Sham acupuncture

One subcutaneous abdominal hematoma

p < 0.008

(1 cycle)

(17)

3

Hand acupuncture therapy10

10 @ L/FP

7

Not reported

MSSL

3.94 ± 1.66

No treatment received

No serious AE observed

p < 0.001

A5,A6,A8,A12,A16,A18,N18,F6

3/wk, 4 wks

20.63 ± 10.32

(10)

(1 cycle)

4

Hand moxibustion therapy10

10 @ L/FP

8

Not reported

MSSL

3.40 ± 1.78

No treatment received

None reported

p < 0.001

A5,A6,A8,A12,A16,A18,N18,F6

3/wk, 4 wks

20.65 ± 6.12

(10)

(1 cycle)

5

Back-Shu points11

30 @ LP

20

Not reported

Met Chinese standards for diagnosis for PMS

Better than CG

Standard acupuncture

None reported

p < 0.05

BL15,17,18,20,21,23

7/wk

score n/a

(20)

(3 cycles)

6

Point-through-point12

30 @ LP

30

Not reported

Diagnosed for PMS by OB/GYN textbook

Better than CG

Medication - progestin (medroxyprogesterone, 6 mg daily) (30)

None reported

p < 0.05

GV3 ~ 8 BL18 ~ 23 BL47 ~ 52

7/wk

score n/a

(3 cycles)

7

BL17,18,20,23 GV20 CV4,17 SP6 PC6 LR313

30 @ LP

31

Not reported

Diagnosed as DSM-IV-TR

Better than CG

Medication - medroxy-progesterone 4 mg, diazepam 2.5 mg twice daily (31)

None reported

p < 0.05

7/wk

score n/a

(3 cycles)

8

Electroacupuncture on scalp14

30 @ L/FP

35

Not reported

Diagnosed as PMS by OB/GYN textbook

Better than CG

Medication - medroxy-progesterone 4 mg, diazepam 2.5 mg twice daily (35)

None reported

p < 0.05

MS1,5 + MS2,3,4

3/wk

score n/a

(3 cycles)

9

GV20 Ex-HN3,5 SP6,10 + LR3 CV17 LR14 Ex-CA1 CV4 SP9 ST36 CV6 PC6 HT7 BL23 GV4 KI315

21 @ LP

30

Not reported

Met ICD-10 criteria

Better than CG

Sham acupuncture

Two hypo menorrhea during 2nd cycle

p < 0.05

3 ~ 4/wk

score n/a

Selection of points N/A

(3 cycles)

(33)

  1. Literatures yield 9 studies as interventions. It comprises of acupuncture points and technique, treatment sessions marking the period of the session (either at luteal phase (LP) or at both LP and follicular phase as L/FP, Duration of the session as in weeks and by menstrual cycles, Baseline score and the outcome score, the control type, and p-value.
  2. *n/a, not available; NS, not significantly different between groups; CG, control group.