Skip to main content


Figure 4 | BMC Complementary and Alternative Medicine

Figure 4

From: Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model

Figure 4

The effect of GEB extract treatment on each subtype of axial, limb, and orolingual abnormal involuntary movement (AIM) induced by L-DOPA in a PD mouse model bearing 6-OHDA lesions. (A) Axial AIM, (B) limb AIM, (C) orolingual AIM, and (D) locomotive AIM scores were measured on days 2, 5, and 9 after the initial L-DOPA injection. AIM scores were assessed every 20 min over 140 min following L-DOPA administration and were then integrated. *P < 0.05 and **P < 0.01 compared with the LID group.

Back to article page