Table 1 Differentially expressed genes after treatment with Gelsemium s. 2c in SH-SY5Y cells
Gene ID | Transcript ID | Symbol | Log2 fold change | p 1 | Description |
|---|---|---|---|---|---|
7940 | AF000424 | LST1 | -0.84 ± 0.14 | 0.04 | Leukocyte specific transcript 1 |
390113 | NM_001004726 | OR4X1 | -0.83 ± 0.06 | 0.01 | Olfactory receptor, family 4, subfamily X, member 1 |
23746 | AJ830742 | AIPL1 | -0.82 ± 0.16 | 0.04 | Aryl hydrocarbon receptor interacting protein-like 1 |
284498 | AL833920 | C1orf167 | -0.80 ± 0.17 | 0.05 | Chromosome 1 open reading frame 167 |
221191 | AK058068 | Klkbl4 | -0.79 ± 0.12 | 0.04 | Plasma kallikrein-like protein 4 |
26658 | NM_012377 | OR7C2 | -0.77 ± 0.07 | 0.01 | Olfactory receptor, family 7, subfamily C, member 2 |
112401 | BC039318 | BIRC8 | -0.76 ± 0.11 | 0.00 | Baculoviral IAP repeat-containing 8 |
2848 | NM_005298 | GPR25 | -0.75 ± 0.15 | 0.02 | G protein-coupled receptor 25 |
55803 | NM_018404 | ADAP2 | -0.75 ± 0.11 | 0.02 | ArfGAP with dual PH domains 2 |
386676 | NM_198690 | KRTAP10-9 | -0.73 ± 0.12 | 0.04 | Keratin associated protein 10-9 |
4353 | X04876 | MPO | -0.72 ± 0.15 | 0.04 | Myeloperoxidase |
N/A | AY358413 | N/A | -0.71 ± 0.18 | 0.02 | Homo sapiens clone DNA59853 trypsin inhibitor |
392391 | NM_001001923 | OR5C1 | -0.71 ± 0.05 | 0.04 | Olfactory receptor, family 5, subfamily C, member 1 |
N/A | AK094115 | N/A | -0.70 ± 0.11 | 0.04 | Homo sapiens cDNA FLJ36796 fis, clone ADRGL2006817 |
55287 | BC020658 | TMEM40 | -0.70 ± 0.15 | 0.02 | Transmembrane protein 40 |
54209 | NM_018965 | TREM2 | -0.69 ± 0.10 | 0.02 | Triggering receptor expressed on myeloid cells 2 |
150365 | AK097834 | RP5-821D11.2 | -0.68 ± 0.17 | 0.02 | Similar to mouse meiosis defective 1 gene |
400934 | NM_207478 | FLJ44385 | -0.68 ± 0.09 | 0.04 | FLJ44385 protein |
255061 | NM_170685 | TAC4 | -0.67 ± 0.14 | 0.01 | Tachykinin 4 (hemokinin) |
644065 | XM_931993 | LOC644065 | -0.65 ± 0.23 | 0.04 | Hypothetical protein LOC644065 |
1339 | NM_005205 | COX6A2 | -0.64 ± 0.17 | 0.01 | Cytochrome c oxidase subunit VIa polypeptide 2 |
N/A | AK128093 | N/A | -0.63 ± 0.09 | 0.04 | Homo sapiens cDNA FLJ46214 fis, clone TESTI4012623. |
53841 | AY358368 | CDHR5 | -0.63 ± 0.11 | 0.04 | Mucin-like protocadherin |
9332 | NM_004244 | CD163 | -0.63 ± 0.18 | 0.03 | CD163 molecule |
441239 | XM_499305 | LOC441239 | -0.63 ± 0.22 | 0.05 | Hypothetical gene supported by BC063653 |
7164 | NM_001003397 | TPD52L1 | -0.62 ± 0.09 | 0.02 | Tumor protein D52-like 1 |
11136 | NM_014270 | SLC7A9 | -0.62 ± 0.09 | 0.04 | Solute carrier family 7 member 9 |
389084 | NM_206895 | UNQ830 | -0.62 ± 0.11 | 0.04 | ASCL830 |
400224 | XM_375090 | FLJ44817 | -0.62 ± 0.20 | 0.04 | Similar to pleckstrin homology domain protein (5 V327) |
647240 | XM_934559 | LOC647240 | -0.60 ± 0.06 | 0.00 | Hypothetical protein LOC647240 |
846 | BC104999 | CASR | -0.59 ± 0.06 | 0.00 | Calcium-sensing receptor |
116123 | NM_138784 | RP11-45 J16.2 | -0.58 ± 0.09 | 0.04 | Flavin-containing monooxygenase pseudogene |
644280 | XM_497769 | LOC644280 | -0.58 ± 0.06 | 0.05 | Hypothetical protein LOC644280 |
57452 | AB032956 | GALNTL1 | -0.57 ± 0.17 | 0.05 | Alpha-D-galactosamine N-acetylgalactosaminyltransferase |
414301 | NM_001001711 | DDI1 | -0.56 ± 0.11 | 0.04 | DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae) |
116535 | BC016964 | MRGPRF | -0.55 ± 0.17 | 0.01 | MAS-related GPR, member F |
8811 | NM_003857 | GALR2 | -0.55 ± 0.07 | 0.04 | Galanin receptor 2 |
10880 | NM_006686 | ACTL7B | -0.55 ± 0.12 | 0.04 | Actin-like 7B |
6368 | NM_145898 | CCL23 | -0.55 ± 0.11 | 0.05 | Chemokine (C-C motif) ligand 23 |
64581 | BC071746 | CLEC7A | -0.54 ± 0.08 | 0.04 | C-type lectin domain family 7, member A |
644003 | XM_927256 | LOC644003 | -0.54 ± 0.11 | 0.04 | Similar to Mucin-2 precursor (Intestinal mucin 2) |
643514 | XM_931594 | LOC643514 | -0.54 ± 0.10 | 0.03 | Hypothetical protein LOC643514 |
374569 | XM_935431 | LOC374569 | -0.54 ± 0.07 | 0.04 | Similar to Lysophospholipase |
84504 | BC101635 | NKX6-2 | -0.53 ± 0.13 | 0.03 | NK6 transcription factor related, locus 2 (Drosophila) |
732 | NM_000066 | C8B | -0.53 ± 0.06 | 0.05 | Complement component 8, beta polypeptide |
146336 | NM_182510 | FLJ32252 | -0.52 ± 0.03 | 0.01 | Hypothetical protein FLJ32252 |
150763 | BC042847 | LOC150763 | -0.51 ± 0.10 | 0.04 | Hypothetical protein LOC150763 |
2020 | NM_001427 | EN2 | -0.51 ± 0.08 | 0.04 | Engrailed homolog 2 |
646258 | XM_929203 | LOC646258 | -0.51 ± 0.11 | 0.04 | Hypothetical protein LOC646258 |
154872 | NM_001024603 | LOC154872 | 0.51 ± 0.10 | 0.03 | Hypothetical LOC154872 |
400866 | NM_001001789 | C21orf24 | 0.52 ± 0.12 | 0.05 | Chromosome 21 open reading frame 24 |
9457 | NM_020482 | FHL5 | 0.55 ± 0.19 | 0.04 | Four and a half LIM domains 5 |
55816 | NM_018431 | DOK5 | 0.56 ± 0.04 | 0.03 | Docking protein 5 |
1446 | NM_001890 | CSN1S1 | 0.57 ± 0.09 | 0.04 | Casein alpha s1 |
285600 | AK130941 | KIAA0825 | 0.63 ± 0.06 | 0.01 | KIAA0825 protein |
57538 | NM_020778 | ALPK3 | 0.76 ± 0.10 | 0.01 | Alpha-kinase 3 |