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Table 3 Percentage of inhibitions of COX-1 and COX-2 following treatments

From: Ardisia crispa roots inhibit cyclooxygenase and suppress angiogenesis

Concentration (ÎĽg/ml)

Percentage of COX inhibition (%)

COX-1

COX-2

12.5

25

50

100

200

12.5

25

50

100

200

Aspirin

27.778 ± 0.505

36.027 ± 1.347

37.879 ± 0.842

40.067 ± 1.347

46.465 ± 0.505

33.896 ± 1.074

51.380 ± 0.154

54.294 ± 0.307

59.049 ± 0.153

62.423 ± 0.154

Celecoxib

21.212 ± 1.010

23.569 ± 1.347

27.441 ± 1.852

31.818 ± 2.189

32.492 ± 1.179

25.920 ± 0.460

48.160 ± 0.614

52.454 ± 0.614

55.675 ± 1.074

63.650 ± 0.767

ACRH

26.094 ± 0.505

32.492 ± 0.505

34.512 ± 0.169

37.037 ± 0.000

38.215 ± 0.505

25.767 ± 1.534

38.037 ± 0.920

45.399 ± 0.614

49.693 ± 1.227

56.595 ± 0.153

QRF

25.589 ± 3.367

34.848 ± 0.506

35.690 ± 0.674

36.869 ± 2.189

37.710 ± 0.674

29.908 ± 0.460

41.258 ± 0.460

49.693 ± 0.000

51.687 ± 0.460

58.129 ± 0.154

BQ

20.707 ± 0.505

21.380 ± 0.169

25.253 ± 0.337

27.273 ± 0.337

29.125 ± 0.169

27.301 ± 0.000

43.558 ± 1.688

49.233 ± 0.154

57.209 ± 0.921

61.350 ± 1.277

  1. Each concentration in its respective treatment groups were tested for its cyclooxygenase inhibitory activity (COX-1 and COX-2) in triplicate (n = 3).