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Table 2 Minimal inhibitory concentrations (MIC) of amoxicillin and oxacillin alone or in combination with increasing concentrations (0 to 256 μg/ml) of the cranberry PC fraction FC111 against S. aureus ATCC 29213 and MRSA COL

From: In vitro and in vivo antibacterial activities of cranberry press cake extracts alone or in combination with β-lactams against Staphylococcus aureus

S. aureus strains Antibiotic MIC of antibiotic in μg/mL in the presence of an increasing concentration of the cranberry fraction FC111, also in μg/mL (fold decrease in antibiotic MIC)a
   0 32 64 128 256
ATCC 29213 amoxicillin 0.06 0.06 (1×) 0.06 (1×) 0.015 (4×) 0.015 (4×)
MRSA COL   512 4 (128×) 4 (128×) 1 (512×) 1 (512×)
ATCC 29213 oxacillin 0.5 0.06 (8×) 0.03 (16×) 0.03 (16×) 0.03 (16×)
MRSA COL   512 256 (2×) 128 (4×) 32 (16×) 16 (32×)
  1. a Combination of 128 or 256 μg/mL of FC111 with either antibiotic yielded FIC indices of ≤0.25 against all tested strains.