In vitro and in vivo antibacterial activities of cranberry press cake extracts alone or in combination with β-lactams against Staphylococcus aureus

Table 2 Minimal inhibitory concentrations (MIC) of amoxicillin and oxacillin alone or in combination with increasing concentrations (0 to 256 μg/ml) of the cranberry PC fraction FC111 against S. aureus ATCC 29213 and MRSA COL

*S. aureus* strains	Antibiotic	MIC of antibiotic in μg/mL in the presence of an increasing concentration of the cranberry fraction FC111, also in μg/mL (fold decrease in antibiotic MIC)^a
		0	32	64	128	256
ATCC 29213	amoxicillin	0.06	0.06 (1×)	0.06 (1×)	0.015 (4×)	0.015 (4×)
MRSA COL		512	4 (128×)	4 (128×)	1 (512×)	1 (512×)
ATCC 29213	oxacillin	0.5	0.06 (8×)	0.03 (16×)	0.03 (16×)	0.03 (16×)
MRSA COL		512	256 (2×)	128 (4×)	32 (16×)	16 (32×)

^a Combination of 128 or 256 μg/mL of FC111 with either antibiotic yielded FIC indices of ≤0.25 against all tested strains.

ISSN: 2662-7671