Effect of NT on anti-hyperalgesia. Hyperalgesia reaction induced by Mycobacterium tuberculosis was significantly attenuated by the administration of NT-4 (n = 10). Values are shown as means ± SEM. *p < 0.05 vs. hyperalgesia group, **p <0.01 vs. hyperalgesia group. NT has important effects of antihyperalgesic activity in animal models of inflammatory pain.