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Table 1 MICs of the extracts, compounds from Garcinia nobilis, Oricia suaveolens , Balsmocitrus camerunensis and reference drugs on documented strains and clinical MDR isolates

From: Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensis

Tested samplesa Microorganisms, strains and MIC (μg/ml)b
E. coli E. aerogenes K. pneumoniae P. stuartii P. aeruginosa M. tuberculosis
ATCC 10536 AG 100 AG 102 ATCC 13048 CM 64 EA 27 ATCC 11296 KP55 ATCC 29916 NAE 16 PA 01 PA 124 ATCC 27294 MTCS1 MTCS2
Crude extracts                
GNB 64 256 256 256 512 256 128 512 512 - 512 - 128 256 256
OSR 128 512 - 512 - - 256 256 512 256 - - 512 - 512
OSW 128 512 - - - - 128 128 - 128 - - 256 - 512
BCB 512 - - 256 - - 512 512 - - - - - - -
Compounds                
1 256 128 - - - - - - - - - - - - -
2 64 64 128 128 256 64 512 512 256 64 64 128 8 32 8
3 128 128 64 256 - 256 - - - - - - 64 - 128
4 - 64 128 - 256 128 - - - - 256 - 512 - 512
5 64 128 128 - - 512 512 - 512 - 64 128 32 64 64
8 512 128 256 - 512 128 512 - - - - - 128 512 256
9 - 128 256 - 256 256 - - - - - - - - -
10 64 128 256 - - 128 - - 512 - - - 128 - 512
11 128 256 128 - 256 512 512 - - - - 512 - - -
13 512 64 256 - 512 128 256 - - - 128 512 256 512 512
15 128 256 256 - - 256 - - - - - - - - -
16 128 128 - -   512 - - 512 - - - 512 - -
17 - 128 - - - - - - - - - - - - -
18 - 256 - - - 256 - - - 256 - - - - -
19 - 256 - - - - - - - - - - - - -
20 - 512 - - - - - - - - - - - - -
21 512 256 - - - 256 256 - - - - - - - -
22 512 256 256 512 128 - - 512 - - - - - - -
RA <4 16 512 64 - 64 4 32 - 64 128 128 1 128 4
  1. aTested samples [methanol-dichloromethane 1:1 extract of the stem bark of Garcinia nobilis (GNB), the wood (OSW)roots (OSR) of Oricia suaveolens, and stem bark of Balsmocitrus camerunensis (BCB); compounds isolated from the stem bark of Garcinia nobilis (15), Oricia suaveolens woods (611) and roots (1217), and the stem back of Balsmocitrus camerunensis (1822); caroxanthone (1), 4-prenyl-2-(3,7-dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone (2), smeathxanthone A (3), 8-hydroxycudraxanthone G (4), morusignin I (5), stigma-5-en-3-ol (6), 20(29)lupen-2-ol (7), evoxanthine (8), norevoxanthine (9), 1-hydoxy-2,3-dimethoxy-10-methylacridone (10), 1,3-dimethoxy-10-methylacridone (11), kokusaginine (13), 1-hydroxy-4-methoxy-10-methylacridone (15), syringaresinol (16), limonin (17), 1-hydroxy-3,6-dimethoxy-8-methylxanthone (18), xanthoxyletin (19), imperatorin (20), 6,8-dimethoxycoumarin (21), umbelliferone (22)]; RA: reference antibiotics were chloramphenicol for bacteria, isoniazid for M. tuberculosis; b(−): MIC > 512 μg/mL.
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