Table 3 IC50 (μg/mL) values for the in vitro cytotoxic activity of plants crude extracts on five human cancer cell lines
From: In vitro anticancer screening of 24 locally used Nigerian medicinal plants
Species | BT-549 | BT-20 | PC-3 | SW-480 | JURKAT |
|---|---|---|---|---|---|
Allanblackia floribunda | 14.7 ± 0.23 | 48.3 ± 2.90 | 29.4 ± 0.69 | 57.1 ± 1.16 | Nd |
Bidens pilosa | 43.1 ± 6.09 | 53.7 ± 2.16* | 47.7 ± 2.69* | Nd | 75.6 ± 1.06* |
Bryophyllum pinnatum | 48.2 ± 1.56 | 82.4 ± 0.17* | 48.3 ± 1.05* | Nd | Nd |
Byrsocarpus coccineus Bark | 24.6 ± 0.99 | 52.9 ± 4.11* | 43.7 ± 1.02* | Nd | 65.2 ± 0.87* |
Leaves | 18.6 ± 4.85 | 31.3 ± 0.53* | 29.1 ± 0.64* | Nd | 43.4 ± 1.77* |
Cajanus cajan | 56.1 ± 10.09 | 56.8 ± 2.60 | 50.5 ± 0.76 | 52 ± 0.53 | Nd |
Daniellia oliveri | 28.1 ± 0.56 | 153.1 ± 1.56 | 130.0 ± 0.45 | 147.0 ± 0.47 | Nd |
Erythrophleum suaveolens | 0.55 ± 0.18 | 0.50 ± 0.03 | 1.30 ± 0.14 | 0.80 ± 0.11 | 0.20 ± 0.05 |
Hoslundia opposita | 76.4 ± 7.89 | 56.1 ± 1.57 | 59.7 ± 8.11 | Nd | >200 |
Jatropa curcas | L. 21.3 ± 0.38 | 33.4 ± 0.70 | >200 | >200 | >200 |
Landolphia dulcis | 16.3 ± 4.31 | >200 | >200 | >200 | Nd |
Lannea nigritana | 48.2 ± 3.52 | Nd | >200 | Nd | 53.5 ± 0.35* |
Parkia biglobosa | 100.0 ± 0.67 | 125.0 ± 2.21 | 56.1 ± 0.45 | 136.0 ± 0.81 | Nd |
Parkia filicoidea | 149.0 ± 2.65 | >200 | 94.3 ± 0.50 | Nd | Nd |
Pterocarpus santalinoides | 57.9 ± 0.35 | >200 | >200 | >200 | 10.2 ± 0.25 |
Sida acuta | 10.3 ± 0.21 | 41.1 ± 1.05 | 37.1 ± 0.18 | Nd | 42.3 ± 0.79 |
Tetrapleura tetraptera | 9.1 ± 1.40 | 23.1 ± 7.05 | Nd | Nd | 37.5 ± 5.13* |
Vitex doniana Bark | 62.5 ± 0.23 | 171.1 ± 1.33 | >200 | 89.2 ± 6.65 | 84.0 ± 1.13 |
Root | 44.9 ± 0.10 | 152.3 ± 1.22 | 177.3 ± 1.01 | 45.6 ± 1.35 | 43.4 ± 0.64 |