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Table 2 Percent inhibiton values of plants crude extracts on three human cancer cell lines at 20 and 200 μg/ml concentrations

From: In vitro anticancer screening of 24 locally used Nigerian medicinal plants

Species T-549 BT-20 PC-3
  20 μg/ml 200 μg/ml 20 μg/ml 200 μg/ml 20 μg/ml 200 μg/ml
Acanthus montanus 7 ± 5.01 10 ± 3.45 Nd 27 ± 8.38* Nd <5
Allanblackia floribunda 66 ± 6.51* 96 ± 3.48* 21 ± 4.55 80 ± 5.38* 13 ± 0.58 92 ± 5.29*
Amaranthus spinosus 16 ± 3.86 <5 8 ± 1.72 32 ± 8.14 Nd Nd
Bidens pilosa 23 ± 9.50 97 ± 1.63* Nd 93 ± 1.73* 35 ± 1.08 95 ± 1.53
Bryophyllum pinnatum 24 ± 6.08 96 ± 1.68* Nd 81 ± 6.51* Nd 95 ± 1.62*
Byrsocarpus coccineus Bark 20 ± 2.51 100 Nd 93 ± 2.66* Nd 97 ± 6.15*
Leaves 54 ± 1.76 100 Nd 100 Nd 100
Cajanus cajan 9 ± 1.46 99 ± 0.58* <5 99 ± 0.17* 23 ± 1.53 100
Capsicum frutescens <5 10 ± 0.96 <5 39 ± 3.96 11 ± 2.40 41 ± 1.08
Chromolaena odorata 13 ± 4.21 8 ± 3.06 6 ± 0.81 39 ± 2.12 Nd Nd
Crassocephalum crepidioides 14 ± 2.14 51 ± 1.04* Nd 10 ± 5.21 Nd 9 ± 1.01
Daniellia oliveri 35 ± 1.55 97 ± 0.21* <5 66 ± 4.16* 22 ± 10.50 47 ± 5.78
Erythrophleum suaveolens 100 100 100 100 100 100
Hoslundia opposita 19 ± 0.55 96 ± 0.42* Nd 93 ± 1.67* Nd 51 ± 8.21*
Jatropa curcas 45 ± 4.01 100 29 ± 0.61 87 ± 1.52* Nd Nd
Landolphia dulcis 83 ±1.39 100 Nd 11 ± 1.21 Nd 9 ± 3.11
Lannea nigritana 32 ± 0.32 90 ± 0.17* Nd Nd Nd 21 ± 7.71*
Ocimum basilicum <5 <5 <5 <5 <5 Nd
Parkia biglobosa <5 75 ± 3.36* 7 ± 5.13 72 ± 0.61 17 ± 7.21 93 ± 6.03*
Parkia filicoidea <5 67 ± 3.06* <5 27 ± 3.70 10 ± 0.70 76 ± 1.53*  
Pterocarpus santalinoides 17 ± 2.52 98 ± 0.45* <5 11 ± 5.03 <5 17 ± 0.40
Rauvolfia vomitoria <5 37 ± 1.12 19 ± 0.72 33 ± 1.71 <5 8 ± 4.23  
Sida acuta 91 ± 5.86* 95 ± 3.16* 25 ± 5.03 97 ± 0.57* 27 ± 2.20 97 ± 1.80*
Tetrapleura tetraptera 66 ± 1.38* 100 58 ± 9.13* 100 Nd Nd  
Vitex doniana Bark <5 89 ± 1.27* Nd 55 ± 1.33 Nd <5
Root 21 ± 1.46 56 ± 2.35* Nd 61 ± 1.06 Nd 57 ± 1.25
  1. The antiproliferative/cytotoxic effect is expressed in terms of the percent inhibition of cells growth relative to the DMSO control after 72 h exposure to the extracts. Results are expressed as mean ± SD of three rreplicate experiments. Nd = Not determined. *There was a significant difference in cell inhibition in extract-treated cultures compared with DMSO-control in all cell lines (P<0.05).