Table 1 Effect of atropine on the laxative activity of the crude methanolic extract of Viola betonicifolia (VBME) in mice

1

Saline (p.o mL/kg)

10

3 ± 0.36

0

0

2

Atropine (i.p)

10

1 ± 0.63

0

0

3

Carbachol (p.o)

1

11.5 ± 0.5**

10.0 ± 0.54***

88.16 ± 3.07

4

VBME (p.o)

30

8.3 ± 0.88**

5.1 ± 0.9*

61.16 ± 2.18

5

100

11.1 ± 1.3**

9.5 ± 71**

86.83 ± 4.8

6

Carbachol + Atropine (i.p)

1 + 10

4 ± 0.5**

0.83 ± 0.3***

22.5 ± 10.1

7

VBME (p.o) + Atropine (i.p.)

30 + 10

5.3 ± 0.9*

1.83 ± 0.3***

36.6 ± 5.2

8

100 + 10

4.6 ± 0.6**

2 ± 0.36***

46.3 ± 11.7