Quantitative evaluation of the M1 and M2 macrophage/microglia. By immunofluorescence staining, most iNOS or Arg1 were expressed in ED1 positive cells. In LBP-pre groups at 7 d and 14 d, there were elevated ED1 expression, increased ED1+iNOS+ cells and reduced ED1+Arg1+ (M2) cell, in comparison to the controls. LBP-pre treated animals showed an increased number of M2 cells. Bar = 20 μm.