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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: A Chinese herbal formula, Yi-Qi-Fu-Sheng, inhibits migration/invasion of colorectal cancer by down-regulating MMP-2/9 via inhibiting the activation of ERK/MAPK signaling pathways

Figure 2

The Effect of YQFS on apoptosis and the cell cycle in HCT-116 cells. (A) Flow cytometry analysis of the cell cycle distribution of cultured HCT-116 cells with PI staining following 24 h exposure of cells to YQFS. Detection of apoptosis with Annexin V-FITC/PI binding to HCT-116 cells. Viable cells (Annexin V/PI) are located in the lower left, apoptotic cells (Annexin V+/PI) in the lower right, post apoptotic secondary necrotic cells (Annexin V+/PI+) in the upper right and primary necrotic cells (Annexin V/PI+) in the upper left quadrants, respectively. The numbers in each quadrant are the percentages of cells in question. (B) Distribution of HCT-116 cells’ cycle indicated by PI staining. The values shown are the mean ± SEM of 3 experiments. **P < 0.01 vs. the control.

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