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Table 4 Effect of CLRE on OHdG, Nitrotyrosine and MDA from rats at the end of 8 weeks study

From: Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats

Treatment 8-OH-dG (ng/mL) Nitrotyrosine (ng/mL) MDA (nM/mg protein)
Normal rats 2.17 ± 0.33 1.06 ± 0.07 2.17 ± 0.33
Cirrhosis rats 5.40 ± 0.34** 3.87 ± 0.13** 5.40 ± 0.34**
Silymarin-treated Rats 2.80 ± 0.15* 1.67 ± 0.07* 2.80 ± 0.15*
Low Dose CLRE-treated rats (250 mg/kg) 2.83 ± 0.33* 1.40 ± 0.20* 2.83 ± 0.33*
High Dose CLRE-treated rats (500 mg/kg) 2.37 ± 0.88* 1.33 ± 0.13* 2.37 ± 0.88*
  1. Data are expressed as mean ± SEM. *P<0.001 compared with the cirrhosis control Group 2. **P<0.001 compared with normal control Group 1. CLRE: C. longa rhizomes ethanolic extract.