Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats

Table 4 Effect of CLRE on OHdG, Nitrotyrosine and MDA from rats at the end of 8 weeks study

Treatment	8-OH-dG (ng/mL)	Nitrotyrosine (ng/mL)	MDA (nM/mg protein)
Normal rats	2.17 ± 0.33	1.06 ± 0.07	2.17 ± 0.33
Cirrhosis rats	5.40 ± 0.34**	3.87 ± 0.13**	5.40 ± 0.34**
Silymarin-treated Rats	2.80 ± 0.15*	1.67 ± 0.07*	2.80 ± 0.15*
Low Dose CLRE-treated rats (250 mg/kg)	2.83 ± 0.33*	1.40 ± 0.20*	2.83 ± 0.33*
High Dose CLRE-treated rats (500 mg/kg)	2.37 ± 0.88*	1.33 ± 0.13*	2.37 ± 0.88*

Data are expressed as mean ± SEM. *P<0.001 compared with the cirrhosis control Group 2. **P<0.001 compared with normal control Group 1. CLRE: C. longa rhizomes ethanolic extract.

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