Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats

Table 3 Effect of CLRE on liver index measurements from rats at the end of 8 weeks study

Treatment	Body weight (g)	Liver weight (g)	Liver weight × 100/body weight
Normal rats	341.33 ± 6.18	8.43 ± 0.34	2.47 ± 0.06
Cirrhosis rats	216.83 ± 10.96	10.13 ± 0.54	4.70 ± 0.22**
Silymarin-treated rats	336 ± 9.187	9.12 ± 0.34	2.72 ± 0.14*
Low dose CLRE-treated rats (250 mg/kg)	249.17 ± 14.89	8.80 ± 0.29	3.58 ± 0.19*
High dose CLRE-treated rats (500 mg/kg)	351 ± 19.73	9.48 ± 0.19	2.74 ± 0.15*

Data are expressed as mean ± SEM. *P<0.001 compared with the cirrhosis control Group 2. **P<0.001 compared with normal control Group 1. CLRE: C. longa rhizomes ethanolic extract.

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