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Table 3 Percentage inhibition of cancer cell proliferation and IC 50 values

From: Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts - an in vitro study

Sample Type of cell line
  Colo – 205 Y79 HepG2 SupT1
  %age Inhibition IC 50 Value % age Inhibition IC 50 Value % age Inhibition IC 50 Value % age Inhibition IC 50 Value
APE (200 μg/mL) 68.33 ± 1.41* 29.57 ± 2.02 66.40 ± 5.44* 35.94 ± 2.10 53.33 ± 1.21* 44.31 ± 3.07 61.34 ± 1.32* 37.00 ± 2.38
APA (200 μg/mL) 92.25 ± 2.05*** 18.91 ± 1.06 92.80 ± 6.34* 26.74 ± 1.34 88.52 ± 3.04** 27.03 ± 1.03 94.12 ± 3.34** 26.89 ± 3.24
Doxorubicin (Standard) 10 μg/mL 94.81 ± 3.42 0.41 ± 0.08 94.20 ± 4.11 0.39 ± 0.10 89.18 ± 3.42 0.47 ± 0.08 95.20 ± 3.11 0.39 ± 0.11
DMSO 2% (Solvent control) 6.67 ± 1.67 -- 3.33 ± 0.78 -- 3.13 ± 1.01 -- 4.33 ± 0.78 --
  1. Values were the means of four replicates ± standard deviation (SD). Significant p value (*** p < 0.001, ** p < 0.01 and * p <0.05 were obtained by Student’s t test analysis. Composite treatments were compared using one-way analysis of variances (ANOVA) and probability values were found to be equal to or less than 0.05 for all the four cell lines.