Figure 2

GHJTY causes the rearrangement of actin cytoskeleton in HIG-82 cells. HIG-82 cells were treated with GHJTY for 2 days and actin and nucleus were stained with Alexa Fluor 594-conjugated Phalloidin (red color) and DAPI (blue color), respectively. GHJTY caused the disruption of actin filament in HIG-82 cells and the nuclei of the cells to be condensed. The effect of GHJTY was also shown in IL-1β-activated HIG-82 cells.