GHJTY specifically inhibits the proliferation of HIG-82 cells. (A) HIG-82 cells were exposed to IL-1β or GHJTY for 2 days and cell proliferation was assayed by MTS. Proliferation of HIG-82 cells was decreased by Celecoxib (Cel). GHJTY significantly reduced the proliferation of HIG-82 cells at concentrations of 0.3 to 1.0 mg/ml. GHJTY did not show any cytotoxic effect on other origin cells, HeLa and RAW264.7 cells (B and C). ++ P < 0.01: compared with non-treated group, * P < 0.05, ** P < 0.01, and *** P < 0.001: compared with IL-1β treated group.