Figure 2
The effect of blocking the benzodiazepine-GABA (left) or 5-HT 1A (right) receptors on (A) the time (s) spent in the illuminated chamber, (B) the number of transitions between chambers and (C) the number of rearings evaluated in the light/dark box test. The data are presented as the median and interquartile range (Q1-Q3). TW: vehicle, 10 ml/kg (p.o.); DZP: diazepam, 1 mg/kg (i.p.); EO: C. aurantium essential oil, 5 mg/kg (p.o.); FLU: flumazenil, 2.0 mg/kg (i.p.); WAY: WAY100635, 0.5 mg/kg (i.p.). The numbers in brackets indicate the number of mice in each group. *p ≤ 0.05, **p ≤ 0.01 in relation to the TW group; # p ≤ 0.05 between compared groups (Kruskal-Wallis followed by Mann-Whitney U-Test).