Figure 1From: Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment The effect of acute or repeated treatments on (A) the time (s) spent in the illuminated chamber, (B) the number of transitions between chambers and (C) the number of rearings evaluated in the light/dark box test. The data are presented as the median and interquartile range (Q1-Q3). TW: vehicle, 10 ml/kg (p.o.); DZP: diazepam, 1 mg/kg (i.p.); EO: Citrus aurantium essential oil, 1, 5, 10 or 50 mg/kg (p.o.); LIM: d-limonene, 5 mg/kg (p.o.); BUSP: buspirone, 10 mg/kg (i.p.). The numbers in brackets indicate the number of mice in each group. *p ≤ 0.05, **p ≤ 0.01 in relation to the TW group (Kruskal-Wallis followed by Mann-Whitney U-Test).Back to article page