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Table 4 Effect of treatments on peak blood glucose (PBG) and area under the curve (AUC) after starch loading (4 g/kg) in non-diabetic rats (NDRs) and STZ-diabetic rats (SDRs)

From: In vitro and in vivo effects of standardized extract and fractions of Phaleria macrocarpa fruits pericarp on lead carbohydrate digesting enzymes

Group

PBG (mmol/L)

% Reduction of PBG

AUC (mmol/L)

% Reduction of AUC

Non-diabetic rats

    

NC (vehicle)

6.12 ± 0.10

 

11.22 ± 0.17

 

ACAR (10 mg/kg)

4.43 ± 0.11*

27.61

9.10 ± 0.19*

18.89

ME (1 g/kg)

5.78 ± 0.39

5.56

10.37 ± 0.50

7.58

NBF (1 g/kg)

5.18 ± 0.08*

15.36

9.61 ± 0.08

14.35

SFI (1 g/kg)

5.97 ± 0.05

2.45

10.58 ± 0.15

5.70

Diabetic rats

    

DC (vehicle)

22.5 ± 1.02

 

41.2 ± 1.74

 

ACAR (10 mg/kg)

18.7 ± 1.95

16.89

26.1 ± 2.8*

36.65

ME (1 g/kg)

22.6 ± 1.03

-

43.9 ± 2.99

-

NBF (1 g/kg)

21.1 ± 1.38

6.22

35.6 ± 2.32

13.59

SFI (1 g/kg)

19.1 ± 1.00

15.11

33.5 ± 1.5

18.69

  1. Values are the mean ± SEM, n = 6, *P < 0.05 vs. control. NC: Normal control, DC: Diabetic control, ACAR: Acarbose, ME: Methanol extract, NBF: n-Butanol fraction, SFI: Sub-fraction 1.