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Table 2 Effects of polyherbal formulations (ZPTO and ZTO), on blood pressure, serum lipids and glucose levels in SHR

From: Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities

Parameters

WKY

SHR

SHR + 3% ZPTO

SHR + 3% ZTO

Systolic BP (mmHg)

141.7 ± 2.4

200.9 ± 10.4###

174.4 ± 4.49**

173.3 ± 5.4**

Heart Rate (BPM)

312.0 ± 22.2

342.9 ± 6.1#

383 ± 18.9***

349.1 ± 23.9

Total Cholesterol (mg/dl)

117.3 ± 5.1

93.3 ± 8.1#

76.8 ± 11.2

82.83 ± 5.3

HDL-C (mg/dl)

98.28 ± 5.8

70.15 ± 7.7##

66.5 ± 8.3

71.14 ± 4.5

LDL-C (mg/dl)

19.1 ± 3.4

23.13 ± 3.8

18.4 ± 3.6

12.3 ± 3*

Triglycerides (mg/dl)

82.85 ± 3.7

98.0 ± 4.4#

60.5 ± 5.3***

64.2 ± 6.7***

Atherogenic Index

0.20 ± 0.04

0.37 ± 0.09###

0.15 ± 0.04**

0.17 ± 0.03**

Glucose (mg/dl)

113.4 ± 6.1

88 ± 13.6#

80.8 ± 7.8

130.3 ± 17.6**

  1. Wistar Kyoto Rats (WKY), Spontaneously Hypertensive Rats (SHR).
  2. Polyherbal formulations, ZTO and ZPTO are composed of Zingiber officinalis (Z), Terminalia belerica (T), Orchis mascula or/and Piper nigrum (P).
  3. Values shown are Mean ± S.E.M. of 7–8 determinations.
  4. #p <0.05; ##p <0.01; ###p <0.001 compared to WKY (Student t-test).
  5. * p <0.05; ** p <0.01; *** p <0.001 compared to SHR (One-way ANOVA followed by Dunnett’s multiple comparison-test).