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Table 2 Effects of polyherbal formulations (ZPTO and ZTO), on blood pressure, serum lipids and glucose levels in SHR

From: Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities

Parameters WKY SHR SHR + 3% ZPTO SHR + 3% ZTO
Systolic BP (mmHg) 141.7 ± 2.4 200.9 ± 10.4### 174.4 ± 4.49** 173.3 ± 5.4**
Heart Rate (BPM) 312.0 ± 22.2 342.9 ± 6.1# 383 ± 18.9*** 349.1 ± 23.9
Total Cholesterol (mg/dl) 117.3 ± 5.1 93.3 ± 8.1# 76.8 ± 11.2 82.83 ± 5.3
HDL-C (mg/dl) 98.28 ± 5.8 70.15 ± 7.7## 66.5 ± 8.3 71.14 ± 4.5
LDL-C (mg/dl) 19.1 ± 3.4 23.13 ± 3.8 18.4 ± 3.6 12.3 ± 3*
Triglycerides (mg/dl) 82.85 ± 3.7 98.0 ± 4.4# 60.5 ± 5.3*** 64.2 ± 6.7***
Atherogenic Index 0.20 ± 0.04 0.37 ± 0.09### 0.15 ± 0.04** 0.17 ± 0.03**
Glucose (mg/dl) 113.4 ± 6.1 88 ± 13.6# 80.8 ± 7.8 130.3 ± 17.6**
  1. Wistar Kyoto Rats (WKY), Spontaneously Hypertensive Rats (SHR).
  2. Polyherbal formulations, ZTO and ZPTO are composed of Zingiber officinalis (Z), Terminalia belerica (T), Orchis mascula or/and Piper nigrum (P).
  3. Values shown are Mean ± S.E.M. of 7–8 determinations.
  4. #p <0.05; ##p <0.01; ###p <0.001 compared to WKY (Student t-test).
  5. * p <0.05; ** p <0.01; *** p <0.001 compared to SHR (One-way ANOVA followed by Dunnett’s multiple comparison-test).