|
Parameters
|
WKY
|
SHR
|
SHR + 3% ZPTO
|
SHR + 3% ZTO
|
|---|
|
Systolic BP (mmHg)
|
141.7 ± 2.4
|
200.9 ± 10.4###
|
174.4 ± 4.49**
|
173.3 ± 5.4**
|
|
Heart Rate (BPM)
|
312.0 ± 22.2
|
342.9 ± 6.1#
|
383 ± 18.9***
|
349.1 ± 23.9
|
|
Total Cholesterol (mg/dl)
|
117.3 ± 5.1
|
93.3 ± 8.1#
|
76.8 ± 11.2
|
82.83 ± 5.3
|
|
HDL-C (mg/dl)
|
98.28 ± 5.8
|
70.15 ± 7.7##
|
66.5 ± 8.3
|
71.14 ± 4.5
|
|
LDL-C (mg/dl)
|
19.1 ± 3.4
|
23.13 ± 3.8
|
18.4 ± 3.6
|
12.3 ± 3*
|
|
Triglycerides (mg/dl)
|
82.85 ± 3.7
|
98.0 ± 4.4#
|
60.5 ± 5.3***
|
64.2 ± 6.7***
|
|
Atherogenic Index
|
0.20 ± 0.04
|
0.37 ± 0.09###
|
0.15 ± 0.04**
|
0.17 ± 0.03**
|
|
Glucose (mg/dl)
|
113.4 ± 6.1
|
88 ± 13.6#
|
80.8 ± 7.8
|
130.3 ± 17.6**
|
- Wistar Kyoto Rats (WKY), Spontaneously Hypertensive Rats (SHR).
- Polyherbal formulations, ZTO and ZPTO are composed of Zingiber officinalis (Z), Terminalia belerica (T), Orchis mascula or/and Piper nigrum (P).
- Values shown are Mean ± S.E.M. of 7–8 determinations.
-
#p <0.05; ##p <0.01; ###p <0.001 compared to WKY (Student t-test).
-
* p <0.05; ** p <0.01; *** p <0.001 compared to SHR (One-way ANOVA followed by Dunnett’s multiple comparison-test).
