|
Parameters
|
ND
|
AD
|
AD + 3% ZPTO
|
AD + 3% ZTO
|
|---|
|
Total Cholesterol (mg/dl)
|
74.62 ± 3.9
|
390.5 ± 3.09 ###
|
110.3 ± 12.14***
|
110.7 ± 10.24***
|
|
HDL-C (mg/dl)
|
38.54 ± 1.7
|
27.82 ± 2.97
|
30.91 ± 3.1
|
82.6 ± 11.45***
|
|
LDL-C (mg/dl)
|
24.9 ± 2.8
|
304 ± 35.7 ###
|
74.5 ± 9.4***
|
57.24 ± 10.8***
|
|
Triglycerides (mg/dl)
|
59.7 ± 4.2
|
65.2 ± 6.4
|
71.6 ± 11.6
|
49.5 ± 11.8
|
|
Atherogenic Index
|
0.92 ± 0.12
|
16.96 ± 3.15###
|
3.53 ± 0.813**
|
0.7 ± 0.155***
|
|
Glucose (mg/dl)
|
95.6 ± 7.2
|
147.5 ± 4.8 ###
|
94.18 ± 6.96***
|
130.3 ± 3.15**
|
|
Daily diet consumption (g/Kg/day)
|
186.5 ± 11.8
|
161.8 ± 12.4#
|
78.9 ± 10.8***
|
121.9 ± 7.1***
|
|
% Change in body weight
|
33.33 ± 1.6
|
56.8 ± 1.97###
|
53.2 ± 0.8
|
46.51 ± 1.61**
|
- Normal Diet (ND) administered Sprague Dawley rats (SD), Atherogenic Diet (AD) administered SD rats; Polyherbal formulations, ZTO and ZPTO are composed of Zingiber officinalis (Z), Terminalia belerica (T), Orchis mascula, or/and Piper nigrum (P); Values shown are Mean ± S.E.M. of 7–10 determinations.
-
#p <0.05 and ###p <0.001 compared to ND (Student t-test).
-
** p <0.01 and *** p <0.001 compared to AD (One-way ANOVA followed by Dunnett’s multiple comparison-test).
