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Table 3 Effect of oral administration of curcumin for six weeks on lipid peroxidation, reduced glutathione and antioxidant enzyme activities in streptozotocin induced diabetic rats

From: Curcumin regulates gene expression of insulin like growth factor, B-cell CLL/lymphoma 2 and antioxidant enzymes in streptozotocin induced diabetic rats

 

Group I

Group II

Group III

TBARS (μM)

34.6 ± 0.05

42.9 ± 0.1*

32.6 ± 0.09#

CAT (nmol/min/gram tissue)

23.2 ± 0.10

32.6 ± 0.2*

31.1 ± 1.50*

SOD (U/gram tissue)

6.1 ± 0.03

7.2 ± 0.1*

8.3 ± 0.07*#

GPX (nmol/min/ gram tissue)

209.0 ± 1.2

220.4 ± 2.1*

323.0 ± 3.20*#

GST (nmol/min/ gram tissue)

163.0 ± 1.1

175.2 ± 2.0*

260.1 ± 3.10*#

GSH (μM)

4.8 ± 0.2

3.1 ± 0.1*

8.7 ± 0.10*#

  1. Group I (non diabetic), group II (diabetic), group III (diabetic treated with curcumin); Values are mean ± SD of 8 rats; TBARS: thiobarbituric acid reactive substances; CAT: catalase; SOD: superoxide dismutase; GST: glutathione-S transferase; GSH: reduced glutathione.
  2. *Mean values are significantly (P < 0.05) different compare to the control (group I). #Mean values are significantly (P < 0.05) different compare to diabetic rats (group II).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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