Figure 5

Effects of SHSST on liver tissue. (A) mRNA expression of SREBP-2, (B) LXR, (C) LDLR, and (D) HMG-CoA. (E) was Western bolt of SREBP-2. Data were normalized to GAPDH mRNA expression levels and then compared to the values for the CON group, which were assigned a value of 1.0. CON, standard diet group; HC, high-cholesterol diet group; SHSST-L, HC plus 30% ethanol extract of SHSST treatment group; SHSST-H, HC plus 80% ethanol extract of SHSST treatment group. Each bar represents the mean ± SEM value of 2 independent experiments for 10 mice from each group. ^### p < 0.001 vs. control group, ^* p < 0.05 vs. HC group, ^** p < 0.01 vs. HC group, ^*** p < 0.001 vs. HC group.