Skip to main content

Table 2 Antimycobacterial activity (MIC and MBC, μg/ml) of the 18 plant extracts

From: Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents

Plant species

Solvent

Extraction Yields (%)

Minimum inhibitory concentration (μg/ml)

Minimum bactericidal concentration (μg/ml)

H37Rv

H37Ra

Strain 1

Strain 2

H37Rv

H37Ra

Strain 1

Strain 2

Stachy stmolea

PEF

0,59

>6400

>6400

nd

nd

-

-

-

-

EAF

3,02

>6400

>6400

nd

nd

-

-

-

-

MEF

6,52

>6400

>6400

nd

nd

-

-

-

-

Stachys thirkei

PEF

0,41

>6400

>6400

nd

nd

-

-

-

-

EAF

4,87

>6400

>6400

nd

nd

-

-

-

-

MEF

11,21

>6400

>6400

nd

nd

-

-

-

-

Ballota acetabulosa

PEF

0,73

200

400

800

400

800

800

1600

1600

EAF

2,30

>6400

>6400

nd

nd

-

-

-

-

MEF

8,87

>6400

>6400

nd

nd

-

-

-

-

Thymus sibthorpii

PEF

0,61

12,5

50

800

400

800

800

800

800

EAF

3,18

12,5

12,5

400

400

400

400

400

400

MEF

3,85

800

200

1600

800

>6400

>6400

>6400

>6400

Satureja aintabensis

PEF

0,58

25

50

100

100

100

100

100

100

EAF

3,24

12,5

12,5

50

50

50

50

50

50

MEF

6,39

100

400

3200

1600

>6400

>6400

>6400

>6400

Micromeria juliana

PEF

0,29

1600

1600

-

nd*

>6400

>6400

-

-

EAF

2,32

100

50

200

400

>6400

>6400

>6400

>6400

PEF

5,26

1600

1600

-

-

>6400

>6400

-

-

Standard drugs

          

SM

 

0.63

0.63

1.25

0.63

-

-

-

-

INH

 

0.16

0.31

0.31

0.31

1.25

1.25

1.25

1.25

RIF

 

0.78

0.39

0.78

0.78

6.25

3.13

6.25

6.25

EMB

 

2.73

2.73

2.73

1.37

-

-

-

-

  1. Nd, not determined due to the fact that the samples were not active on H37Rv and H37Ra; nd*: not determined due to insufficient amount of the sample;(−) not tested; PEF, Petroleum ether fraction; EAF, Ethyl acetate fraction; MEF, Methanol fraction; SM, Streptomycin; INH, Isoniazid; RIF, Rifampicin; EMB, Ethambutol.