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Table 2 Antimycobacterial activity (MIC and MBC, μg/ml) of the 18 plant extracts

From: Preliminary antimycobacterial study on selected Turkish plants (Lamiaceae) against Mycobacterium tuberculosis and search for some phenolic constituents

Plant species Solvent Extraction Yields (%) Minimum inhibitory concentration (μg/ml) Minimum bactericidal concentration (μg/ml)
H37Rv H37Ra Strain 1 Strain 2 H37Rv H37Ra Strain 1 Strain 2
Stachy stmolea PEF 0,59 >6400 >6400 nd nd - - - -
EAF 3,02 >6400 >6400 nd nd - - - -
MEF 6,52 >6400 >6400 nd nd - - - -
Stachys thirkei PEF 0,41 >6400 >6400 nd nd - - - -
EAF 4,87 >6400 >6400 nd nd - - - -
MEF 11,21 >6400 >6400 nd nd - - - -
Ballota acetabulosa PEF 0,73 200 400 800 400 800 800 1600 1600
EAF 2,30 >6400 >6400 nd nd - - - -
MEF 8,87 >6400 >6400 nd nd - - - -
Thymus sibthorpii PEF 0,61 12,5 50 800 400 800 800 800 800
EAF 3,18 12,5 12,5 400 400 400 400 400 400
MEF 3,85 800 200 1600 800 >6400 >6400 >6400 >6400
Satureja aintabensis PEF 0,58 25 50 100 100 100 100 100 100
EAF 3,24 12,5 12,5 50 50 50 50 50 50
MEF 6,39 100 400 3200 1600 >6400 >6400 >6400 >6400
Micromeria juliana PEF 0,29 1600 1600 - nd* >6400 >6400 - -
EAF 2,32 100 50 200 400 >6400 >6400 >6400 >6400
PEF 5,26 1600 1600 - - >6400 >6400 - -
Standard drugs           
SM   0.63 0.63 1.25 0.63 - - - -
INH   0.16 0.31 0.31 0.31 1.25 1.25 1.25 1.25
RIF   0.78 0.39 0.78 0.78 6.25 3.13 6.25 6.25
EMB   2.73 2.73 2.73 1.37 - - - -
  1. Nd, not determined due to the fact that the samples were not active on H37Rv and H37Ra; nd*: not determined due to insufficient amount of the sample;(−) not tested; PEF, Petroleum ether fraction; EAF, Ethyl acetate fraction; MEF, Methanol fraction; SM, Streptomycin; INH, Isoniazid; RIF, Rifampicin; EMB, Ethambutol.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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