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Table 2 Concentrations of five Helichrysum zivojinii extracts, which induced 50% decrease in the target cancer cell survival, determined by MTT test

From: In vitro antitumor actions of extracts from endemic plant Helichrysum zivojinii

 

HeLa

Fem-x

K562

MDA-MB-361

Extract 1 IC 50 [μg/ml]

24.63 ± 4.12

28.85 ± 5.49

11.78 ± 0.94

81.74 ± 6.27

Extract 2 IC 50 [μg/ml]

20.11 ± 4.49

23.64 ± 1.41

23.82 ± 6.54

81.74 ± 13.31

Extract 3 IC 50 [μg/ml]

37.98 ± 2.33

47.04 ± 4.79

27.52 ± 4.96

79.93 ± 13.49

Extract 4 IC 50 [μg/ml]

56.70 ± 6.05

74.84 ± 7.55

50.37 ± 3.28

69.96 ± 11.70

Extract 5 IC 50 [μg/ml]

84.68 ± 10.39

77.29 ± 6.55

74.88 ± 7.57

94.92 ± 6.85

Cisplatin IC 50 [μM]

5.60 ± 1.41

5.02 ± 0.59

5.35 ± 0.70

28.23 ± 5.04

  1. Time of continuous agent’s action was 72 h.