Figure 2

The effect of selected receptor antagonists on FDA-induced uterine contraction. (a) Representative tracings of isometric uterine contraction following FDA administration in the presence of various antagonists and (b) mean Emax following administration of FDA at 2 mg/ml and in the presence of atropine, THG113.31 and atosiban. Atropine caused the least inhibition while atosiban produced the greatest inhibition on the Emax. Concomitant administration of all three antagonists resulted in a remarkable decrease in the Emax. n = 6 rats per group, *p < 0.05.