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Table 4 Area under the Curve (AUC) for short-term effects, before to 0 minutes after intervention

From: Short- and long-term effects of tactile massage on salivary cortisol concentrations in Parkinson’s disease: a randomised controlled pilot study

  Group AUC screening 1 AUC intervention 2 p-value3
First intervention RTM 553 (175-1118) 350 (143-1271) 0.249
  TM 571 (219-1226) 456 (189-954) 0.153
Eighth intervention RTM 563 (188-1117) 338 (173-1030) 0.035*
  TM 525 (242-1215) 352 (221-656) 0.003*
  1. 1 AUC estimated according to individual intervention time for start and duration in minutes based on linear equation for daily AUC at screening. Median (10th and 90th perc).
  2. 2 AUC according to intervention duration and salivary concentration at start, 0 min after and 30 min after. Median (10th and 90th perc).
  3. 3 AUC intervention compared to AUC screening, Wilcoxon’s test for paired data.
  4. *Statistically significant difference.