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Table 2 Baseline variables and cortisol concentrations at first and eighth intervention split by arms

From: Short- and long-term effects of tactile massage on salivary cortisol concentrations in Parkinson’s disease: a randomised controlled pilot study

 

RTM

(n = 14)

TM

(n = 28)

Age (year)

62.5

(54–73)

66.0

(61–73)

Gender (m/f)

6/8

10/18

Time of wakening

  

First/eighth intervention

04.30-07.30

02.00-07.30

04.30-08.00

04.00-08.00

Time of sampling

  

First/eighth intervention

07.20-15.35

08.00-15.49

08.00-15.12

07.51-15.15

Time interval after wakening (min)

90-585

110-543

55-578

40 §-555

Cortisol (nmol/L) (median/10/90%)

  

Before first/eighth intervention

7.0

(4.5/23.9)

9.2

(4.1/17.0)

7.2

(4.1/23.9)

7.5

(4.5/13.8)

After 0′

6.3

(2.6/18.7)

6.8

(2.5/15.4)

6.6

(2.5/11.0)

5.7

(3.5/9.8)

After 30′

6.6

(2.4/8.3)

5.6

(2.6/13.2)

4.8

(2.5/21.1)

4.6

(2.6/9.2)

Delta Cortisol (nmol/L)

    

Before - after 0′

    

First/eighth intervention

1.8

(-3.0/+5.5)

1.9

(-2.0/+6.2)

2.6

(-2.5/+17.1)

1.7

(-2.0/+5.4)

Before- after 30′

    

First/eighth intervention

2.4

(-0.3/+17.1)

3.4

(-2.2/+6.5)

3.6

(-0.1/+13.2)

3.1

(-2.8/+7.5)

Percentage difference in Cortisol

  

Before - after 0′

  

First/eighth intervention

26.8

(-41.0/+42.4)

27.7

(-2.2/+55.4)

38.8

(-38.5/+58.8)

26.1

(-30.9/+53.8)

Before- after 30′

    

First/eighth intervention

45.8

(-4.5/+71.5)

33.3

(-12.9/+60.7)

11.3

(-45.5/+29.2)

11.6

(-28.0/+43.7)

Cortisol AUC G

    

Before - after 0′

    

First/eighth intervention

350

(143/1271)

456

(189/954)

338

(173/1030)

352

(221/656)

Before- after 30′

    

First/eighth intervention

582

(255/1939)

662

(267/1366)

562

(262/1614)

491

(303/854)

  1. Footnote: TM = Tactile massage, RTM = Rest to music. AUCG = area under curve from ground level.
  2. Statistical methods used; Mann–Whitney-U, Chi-2-test, Median test and Kruskal-Wallis test. There were no statistical differences between groups. Eight time intervals < 60 min. at 8th intervention and once at first intervention. §This patient had concentrations, 7.7, 9.7, and 10.2 nmol/L, excluding a cortisol arousal reaction (CAR).