From: Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants
Tested samples | Sample code | Cell lines, IC50(μg/mL ) and degree of resistance* | |||||||
---|---|---|---|---|---|---|---|---|---|
 |  | MDA-MB-231/pcDNA | MDA-MB-231/BCRP | HCT116p53 +/+ | HCT116p53 -/- | U87MG | U87MGΔEGFR | HepG2 | AML 12 |
Haplophyllum tuberculatum | SY177 | 11.92 | 26.65 (2.24) | 2.42 | 3.30 (1.36) | 15.03 | 27.67 (1.84) | 31.64 | - |
Pulicaria crispa | SY179 | 14.6 | 8.37 (0.57) | 2.79 | 2.58 (0.92) | 4.31 | 27.46 (6.37) | 27.85 | - |
Anthemis deserti | SY185 | - | - | 24.48 | 31.94 (1.30) | - | - | - | - |
Ziziphus nummularia | SY188 | - | - | - | - | - | - | - | - |
Neurada procumbens | SY189 | - | - | - | - | 3.01 | - | - | - |
Artemisia monosperma | SY198 | - | 26.16 (<0.65) | 7.35 | 6.65 (0.90) | 25.25 | 24.95 (0.99) | - | - |
Ononis serrata | SY160 | 19.28 | 25.09 (1.30) | 14.9 | 21.94 (1.47) | 28.58 | 31.09 (1.09) | - | - |
Achillea beiberstenii | SY-200 | 10.48 | 22.32 (2.13) | 17.09 | 17.31 (1.01) | - | 19.24 (<0.48) | 27.28 | - |
Doxorubicin | Â | 1.10 | 7.83 (7.12) | 1.41 | 4.06 (2.88) | 1.06 | 6.11 (5.76) | 1.41 | - |