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Table 4 Activities of caspase-3, -8 and -9 in MCF-7 cells treated with C. sativum root extract

From: Antioxidant activity of Coriandrum sativum and protection against DNA damage and cancer cell migration

Treatment Fold change compared to control
Caspase-3 Caspase-8 Caspase-9
Control 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
6 h    
200 μg/ml 0.87 ± 0.02 0.83 ± 0.00 0.84 ± 0.03
276 μg/ml 0.86 ± 0.03 0.87 ± 0.03 0.88 ± 0.04
Positive control 0.91 ± 0.01 0.87 ± 0.01 0.87 ± 0.02
24 h    
200 μg/ml 1.20 ± 0.02* 1.16 ± 0.02* 1.12 ± 0.03*
276 μg/ml 1.28 ± 0.02* 1.21 ± 0.03* 1.30 ± 0.01*
Positive control 1.06 ± 0.01* 1.06 ± 0.02* 1.07 ± 0.02*
  1. The positive controls used were colchicine (caspase-3) and mitomycin C (caspase-8 and -9) at 1 μM.
  2. Values are expressed as fold change compared to control, mean ± SD (n = 3).
  3. *Values are significantly different at P < 0.05 compared to control as tested by the Student’s t-test.