Skip to main content

Table 3 Summary of the results of PS exposure apoptosis assay, Caspase-3/7 activity, MMP changes, PARP-1 and Caspase-8 cleavage, full-length Caspase-9 and γH2Ax protein expression in HeLa cells treated with 500 μg/mL concentration of extracts

From: Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts

Extract PS exposure (percentage of stained cells) Caspase-3/7 activity (fold change) MMP PARP-1 cleavage γH2Ax Caspase-9 reduction Caspase-8 cleavage
P3-86A + (73.95%) + (1.7) + + - - +
K30 + (86.74%) + (50.0) - - + + -
P3-37B + (84.89%) + (4.2) - + + + +
K18 + (85.85%) + (5.9) - + + + +
P3-86B(2) + (80.01%) + (282.1) + + + + +
P3-37C + (84.77%) + (229.7) - + + + +
  1. ‘+’ represents a positive observation, whereas ‘-’represents a negative observation.