MMP changes in HeLa cells after treatment with marine bacterial extracts. Cells were treated with 500 μg/mL of each extract for 12 and 16 h and stained with 50 μM JC-1 and analyzed by flow cytometry. Figure presents the 2D plots of FL-2H vs. FL-1H indicating percentage of cells (± S.D) with intact (red) or permeable (green) mitochondrial membranes. Untx represent untreated sample and 100 mM H2O2 was used as a positive control. The Z- factor was calculated to be 0.79 and 0.80 for 12 h and 16 h time points, respectively.