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Table 5 Comparison of IC 50 values for HepG2 and WRL 68 cells obtained from MTT assay following exposure to VN extract for 24,48 and 72 hours

From: PASS-predicted Vitex negundo activity: antioxidant and antiproliferative properties on human hepatoma cells-an in vitro study

Cell line

Extract

Duration(Hour)

IC50μg/ml

WRL 68

VN

24

>100 a

48

>100 a

72

>100 a

Hep G2

VN

24

66.46 ± 2.8

48

57.36 ± 1.3

72

65.12 ± 1.8

  1. The IC50 value is defined as the concentration of sample necessary to inhibit 50% of the cells. aValue not reach 50% inhibition. IC50 is determined by using Masterplex 2010 software (5Parameters logistics).