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Table 5 Comparison of IC 50 values for HepG2 and WRL 68 cells obtained from MTT assay following exposure to VN extract for 24,48 and 72 hours

From: PASS-predicted Vitex negundo activity: antioxidant and antiproliferative properties on human hepatoma cells-an in vitro study

Cell line Extract Duration(Hour) IC50μg/ml
WRL 68 VN 24 >100 a
48 >100 a
72 >100 a
Hep G2 VN 24 66.46 ± 2.8
48 57.36 ± 1.3
72 65.12 ± 1.8
  1. The IC50 value is defined as the concentration of sample necessary to inhibit 50% of the cells. aValue not reach 50% inhibition. IC50 is determined by using Masterplex 2010 software (5Parameters logistics).