Skip to main content

Table 2 Part of PASS for VN chemical compounds

From: PASS-predicted Vitex negundo activity: antioxidant and antiproliferative properties on human hepatoma cells-an in vitro study

  Biological activity
Compound Lipid peroxidation inhibitor Antioxidant Free radical scavengers Hepatoprotectant Caspase-3 stimulant Antiproliferative
  Pa Pi Pa Pi Pa P Pa Pi Pa Pi Pa Pi
1 0.813 0.003 0.699 0.004 0.786 0.003 0.717 0.007 0.741 0.009 0.737 0.012
2 0.765 0.004 0.671 0.004 0.765 0.003 0.744 0.006 0.706 0.011 0.754 0.011
3 0.798 0.004 0.749 0,004 0.849 0.002 0.741 0.006 0.778 0.007 0.886 0.005
4 0.711 0.005 0.644 0.004 0.751 0.003 0.658 0.009 0.734 0.009 0.855 0.005
5 0.952 0.002 0.874 0.003 0.973 0.001 0.912 0.002 0.812 0.005 0.817 0.007
6 0.304 0.062 0.788 0.003 0.518 0.009 0.983 0.001 0.679 0.012 0.445 0.005
7 0.415 0.031 0.598 0.005 0.698 0.004 0.986 0.001 0.611 0.006 0.554 0.014
8 0.920 0.002 0.798 0.003 0.956 0.001 0.924 0.002 0.749 0.008 0.715 0.013
  1. Pa—probability “to be active”; Pi—probability “to be inactive”.
  2. (1) 5-hydroxy-7,4′dimethoxy flavones, (2) 5-hydroxy-3,6,7,3′,4′-Pentamethoxy flavones, (3) 5, 3′ dihydroxy-7, 8,4′-trimethoxy flavanone, (4) 5,7-dihydroxy-6,4′dimethoxy flavanone, (5) 7,8-dimethyl herbacetin 3-rhamnoside, (6) Agnuside, (7) Negundoside, (8) Vitegnoside.