|
Genotype and allele
|
ABB group (n= 106)
|
nABB group (n= 89)
|
Control group (n= 50)
|
χ2
|
P value
|
|---|
|
n (%)
|
n (%)
|
n (%)
|
|---|
|
5-HT2A A-1438G
| | | | | |
|
Genotype AA
|
34(32.1)
|
29(32.6)
|
18(36.0)
|
13.31
|
0.01
|
|
AG
|
67(63.2)
|
45(50.6)
|
21(42.0)
|
|
GG
|
5(4.7)
|
15(16.9)
|
11(22.0)
|
|
P value
|
0.002a
|
0.59
| | | |
|
Alleles A
|
135(63.7)
|
103(57.9)
|
57(57.0)
|
1.9
|
0.39
|
|
G
|
77(36.3)
|
75(42.1)
|
43(43.0)
|
|
P value
|
0.26
|
0.89
| | | |
|
5-HT2A T102C
| | | | | |
|
Genotype TT
|
34(32.1)
|
30(33.7)
|
19(38.0)
|
15.69
|
0
|
|
TC
|
68(64.2)
|
45(50.6)
|
20(40.0)
|
|
CC
|
4(3.8)
|
14(15.7)
|
11(22.0)
|
|
P value
|
0.000b
|
0.44
| | | |
|
Alleles T
|
136(64.2)
|
105(59.0)
|
58(58.0)
|
1.57
|
0.46
|
|
C
|
76(35.8)
|
73(41.0)
|
42(42.0)
|
|
P value
|
0.3
|
0.87
| | | |
|
BDNF Val66Met
| | | | | |
|
Genotype Val/Val
|
51(48.1)
|
35(39.3)
|
12(24.0)
|
17.79
|
0
|
|
Met/Val
|
51(48.1)
|
42(47.2)
|
26(52.0)
|
|
Met/Met
|
4(3.8)
|
12(13.5)
|
12(24.0)
|
|
P value
|
0.040c
|
0.11
| | | |
|
Alleles Val
|
153(72.2)
|
112(63.0)
|
50(50.0)
|
14.77
|
0
|
|
Met
|
59(27.8)
|
66(37.0)
|
50(50.0)
|
|
P value
|
0.000d
|
0.04
| | | |
|
5-HT1A C-1019G
| | | | | |
|
Genotype CC
|
46(43.4)
|
40(45.0)
|
15(30.0)
|
14.63
|
0.01
|
|
CG
|
55(51.9)
|
35(39.3)
|
23(46.0)
|
|
GG
|
5(4.7)
|
14(15.7)
|
12(24.0)
|
|
P value
|
0.001e
|
0.19
| | | |
|
Alleles C
|
147(69.3)
|
115(64.6)
|
53(53.0)
|
7.91
|
0.02
|
|
G
|
65(30.7)
|
63(35.4)
|
47(47.0)
|
|
P value
|
0.005f
|
0.06
| | | |
-
aOdds ratio (and 95% confidence interval) for GG vs (A/G + A/A) is 0.176(0.057 ~ 0.538), χ2= 11.O25, df= 1, P= 0.001.
-
bOdds ratio (and 95% confidence interval) for CC vs (T/C + T/T) is 0.139(0.042 ~ 0.463), χ2= 12.987, df= 1, P= 0.000.
-
cOdds ratio (and 95% confidence interval) for Val/Val vs (Val/Met + Met/Met) is 2.936(1.383 ~ 6.232), χ2= 8.205, df= 1, P= 0.004, and Met/Met vs Val/Met + Val/Val is 0.124(0.038 ~ 0.409), χ2= 15.100, df= 1, P= 0.000.
-
dOdds ratio (and 95% confidence interval) for Met allele vs Val allele is 2.936(1.383 ~ 6.232), χ2= 14.692, df= 1, P= 0.000.
-
eOdds ratio (and 95% confidence interval) for GG vs (G/C + C/C) is 0.157(0.052 ~ 0.475), χ2= 13.010, df= 1, P= 0.000.
-
fOdds ratio (and 95% confidence interval) for C allele vs G allele is 2.006(1.229 ~ 3.271), χ2= 7.884, df= 1, P= 0.005.
