Microscopic observations of untreated and treated liver of rats. A) Normal, B) Section of liver tissue of 3 g/kg paracetamol-treated group (p.o) showing massive coagulative necrosis, haemorrhage and inflammation. C) Section of 200 mg/kg of silymarin liver tissue pretreated on the liver followed by paracetamol showing preservation of normal hepatocytes. D) Section of pre-treated 50 mg/kg MEMM liver tissue followed by paracetamol showing tissue necrosis, inflammation and haemorrhage. E) Section of pre-treated 250 mg/kg MEMM liver tissue followed by paracetamol showing mild haemorrhage and inflammation. F) Section of pre-treated 500 mg/kg MEMM followed by paracetamol showing normal histology with mild inflammation. (40x magnification). CV – central vein; CN – coagulative necrosis; I – inflammation; H – haemorrhage.