Figure 2

The effect of Dangui-Jakyak-San (DJS) on ischemia-induced memory impairment. To test the effect of DJS on ischemia-induced memory impairment, Morris water maze test was conducted after ischemic injury. Ischemic brain injury was induced by bilateral common carotid artery occlusion (BCCAO). (A) Experimental schedule. (B-D) The effect of DJS on the Morris water maze task. Path length (B) and swimming speed (C) were recorded during the training trials. Swimming time in target quadrant which platform was previously existed (D) was recorded in the probe trial. Data are presented as mean ± S.E.M (n = 10/group). *P < 0.05, compared with sham group. #P < 0.05, compared with BCCAO group (two-way ANOVA followed by Bonferroni’s post-hoc test for B and C, one-way ANOVA followed by Student Newman-Keuls’s post-hoc test for D).