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Table 6 Cytotoxic activity (IC 50 μg/ml) of A. scabra pseudo stem extracts

From: Cytotoxic effect of Alpinia scabra (Blume) Náves extracts on human breast and ovarian cancer cells

Extracts

Treatment duration (hour)

IC50 a(μg/ml) (SIb)

MCF7

SKOV-3

MRC-5

Methanol

24

>100

>100

>100

48

>100

>100

>100

72

>100

>100

>100

Hexane

24

>100

40.67 ± 3.51

>100

48

84.00 ± 1.00

34.00 ± 1.73

55.86 ± 16.71

72

67.30 ± 1.15

34.67 ± 0.58

49.74 ± 1.33

Chloroform

24

80.00 ± 15.10

56.00 ± 5.29

>100

48

66.67 ± 1.16

30.67 ± 5.13

52.86 ± 1.75

72

59.30 ± 1.15

33.00 ± 1.73

48.18 ± 2.34

Water

24

>100

>100

>100

48

>100

>100

>100

72

>100

>100

>100

Doxorubicinc

24

2.50 ± 0.10

2.50 ± 0.10

>100

48

2.37 ± 0.23 (32.4)

1.77 ± 0.15 (43.4)

76.87 ± 12.64

72

0.39 ± 0.02 (4.3)

1.47 ± 0.15 (1.1)

1.68 ± 0.42

  1. aData are presented as mean ± SD from three independent experiments triplicate for each. Values in bold characters are considered to have cytotoxic activity (IC5020 μg/ml or less); bSelectivity Index (SI); cPositive control.