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Table 5 Effect of one week of turmerone administration (2.5, 5.0 mg/kg, p.o.) on MAO-A activity in different regions of the mouse brain

From: Antidepressant-like activity of turmerone in behavioral despair tests in mice

Groups Activity of MAO-A (U·h-1·mg-1)
  Cortex Striatum Hippocampus Hypothalamus
Control 11.4 ± 1.1 22.6 ± 3.0 29.6 ± 1.0 40.0 ± 1.9
Turmerone 2.5 mg/kg 8.1 ±0.8** 22.2 ± 0.6 24.8 ± 1.2 36.6 ± 1.7
Turmerone 5.0 mg/kg 7.0 ± 0.3** 22.4 ± 0.6 22.7 ± 0.9* 37.2 ± 4.3
  1. Values were the means ± SEM (n = 10). * p < 0.05, ** p < 0.01 as compared with the control group. (One-way ANOVA followed by Scheffe’s test).