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Table 5 Effect of one week of turmerone administration (2.5, 5.0 mg/kg, p.o.) on MAO-A activity in different regions of the mouse brain

From: Antidepressant-like activity of turmerone in behavioral despair tests in mice

Groups

Activity of MAO-A (U·h-1·mg-1)

 

Cortex

Striatum

Hippocampus

Hypothalamus

Control

11.4 ± 1.1

22.6 ± 3.0

29.6 ± 1.0

40.0 ± 1.9

Turmerone 2.5 mg/kg

8.1 ±0.8**

22.2 ± 0.6

24.8 ± 1.2

36.6 ± 1.7

Turmerone 5.0 mg/kg

7.0 ± 0.3**

22.4 ± 0.6

22.7 ± 0.9*

37.2 ± 4.3

  1. Values were the means ± SEM (n = 10). * p < 0.05, ** p < 0.01 as compared with the control group. (One-way ANOVA followed by Scheffe’s test).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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