Evaluation of antihyperglycemic and antinociceptive activity of Xanthium indicum stem extract in Swiss albino mice

Table 2 Antinociceptive effect of crude methanol extract of X. indicum stems (XISE) in the acetic acid-induced gastric pain model mice

Treatment	Dose (mg/kg body weight)	Mean number of abdominal constrictions	% inhibition
Control (Group 1)	10 ml	4.8 ± 0.20	-
Aspirin (Group 2)	200 mg	3.0 ± 0.55	37.5*
(XISE)	50 mg	2.8 ± 0.86	41.7*
(XISE)	100 mg	2.4 ± 1.08	50.0*
(XISE)	200 mg	2.2 ± 1.16	54.2*
(XISE)	400 mg	2.0 ± 0.84	61.0*

All administrations (aspirin and extract) were made orally. Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to control.

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