Cytotoxicity of POCU1b. (A) 3 T3-L1 differentiation. (B) Cytotoxicity of POCU1b using the CCK-8 kit. Cells were treated with different concentrations of POCU1b for 5 or 12 days. Data are expression as the mean ± S.E.M. (n = 4). (C) Cytotoxicity at high concentrations of POCU1b. Cells were treated with high concentrations of POCU1b (~200 μg/mL) for 12 days. Data are expression as the mean ± S.E.M. (n = 6).*p < 0.05, **p < 0.01 vs. untreated cells.