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Table 2 Effect of various pharmacological interventions on serum and tissue biochemical parameters

From: Possible modulation of FAS and PTP-1B signaling in ameliorative potential of Bombax ceiba against high fat diet induced obesity

Serum biochemical parameters

Group:

NC

HFD control

B.C. 100

B.C. 200

B.C. 400

Gem.50

Glucose (mg/dl)

93.65 ± 13.46

202.25 ± 4.16a

177.77 ± 14.1b

95.8 ± 9.42b,c

90.8 ± 6.83b,c

100.3 ± 5.97b

TG (mg/dl)

78.9 ± 11.7

195.54 ± 10.63a

138.94 ± 5.8b

114.9 ± 11.75b,c

98.7 ± 7.83b,c

128.4 ± 15.3b

TC (mg/dl)

57.9 ± 4.8

343.42 ± 15.54a

169.889 ± 9.81b

95 ± 6.1b,c

93.12 ± 7.9b,c

94.93 ± 7.3b

LDL (mg/dl)

8.99 ± 5.42

289.76 ± 15.2a

120.83 ± 8.95b

26.45 ± 5.65b,c

13 ± 4.36b,c

15.1 ± 6.9b

VLDL (mg/dl)

15.78 ± 2.3

39.11 ± 2.12a

27.79 ± 1.17b

22.98 ± 2.4b,c

19.74 ± 1.6b,c

25.7 ± 3.1b

HDL (mg/dl)

33.13 ± 5.5

14.55 ± 1.9a

21.28 ± 5.84b

45.57 ± 8.4b,c

60.37 ± 3.1b,c

54.14 ± 5.1b

ALT (IU/L)

50.75 ± 6.6

153.26 ± 7.35a

94.28 ± 5.65b

67.9 ± 4.9b,c

50.8 ± 4.9b,c

71.8 ± 4.64b

AST (IU/L)

66.4 ± 6.7

160.83 ± 6.56a

107.86 ± 9.6b

65.38 ± 7.1b,c

50.25 ± 5.1b,c

87.5 ± 12.4b

Tissue biochemical parameters

TBARS

0.6 ± 0.31

4.93 ± 0.64a

3.9 ± 0.77b

1.83 ± 0.7b,c

1.53 ± 0.7b,c

4.03 ± 0.71b

Nitrite/nitrate

0.74 ± 0.4

2.6 ± 0.1a

1.63 ± 0.04b

0.98 ± 0.1b,c

0.89 ± 0.69b,c

1.61 ± 0.02b

Glutathione

2.05 ± 0.25

0.19 ± 0.8a

0.42 ± 0.07b

1.8 ± 0.21b,c

1.99 ± 0.16b,c

0.55 ± 0.11b

  1. Results were expressed as mean ± SD; ap < 0.05 vs NC, bp < 0.05 vs HFD control, cp < 0.05 vs Gem.50.