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Table 4 Different types of chromosomal damage induced by MMS (40 mg/kg b. w.) and different extracts (300 mg/kg b.w.) from Cyperus rotundus in bone marrow cells of male Balb/c mice

From: Pharmacological, antioxidant, genotoxic studies and modulation of rat splenocyte functions by Cyperus rotundus extracts

Treatment

ctb

csb

del

r

cf

ra

Total aberrationsa

Solvent control : Tween-80 (1%)

-

1

-

6

6

-

13 ± 0.58

Methyl methansulfonate (MMS)

-

16

-

17

12

-

44 ± 3.06

TOF enriched extract

-

3

-

3

3

-

9 ± 1.53

Aqueous extract

-

4

-

4

2

-

10 ± 0.62

Methanolic extract

-

-

-

3

11

-

14 ± 0,58

Solvent control : Tween-80 (5%)

-

-

-

10

7

-

17 ± 1.15

Ethyl acetate extract

-

2

-

12

5

-

19 ± 1.53

  1. ctb = chromatid break, csb = chromosome break, del = deletion, r = ring, cf = centric fusion, ra = rearrangements.
  2. aTotal aberrations (mean ± standard error of the mean from one hundred cells were analyzed per animal for a total of 500 cells per treatment).