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Table 3 Effect of the extracts from Cyperus rotundus on xylene-induced ear edema in mice

From: Pharmacological, antioxidant, genotoxic studies and modulation of rat splenocyte functions by Cyperus rotundus extracts

Treatment

Doses (mg/kg)

Edema (mg)a

Inhibition (%)

Control

-

61,12 ± 7,44

-

Dexamethasone

50

49,46 ± 1,95*

19,08

150

37,9 ± 2,57*

38,48

300

19,06 ± 1,61*

68,81

TOF enriched extract

50

37,46 ± 4,7*

38,71

150

25,38 ± 3,35*

58,47

300

13,9 ± 1,79*

77,25

Aqueous extract

50

42,52 ± 2,72*

30,43

150

28,9 ± 2,01*

52,71

300

15,66 ± 1,05*

74,38

Ethyl acetate extract

50

35,26 ± 1,97*

40,77

150

30,24 ± 1,33*

50,52

300

22,78±1,19*

62,73

Methanolic extract

50

50,76 ± 3,48*

16,95

150

44,98 ± 3,05*

26,41

 

300

33,86 ± 2,10*

44,6

  1. a Values are expressed as mean ± standard deviation (n = 5 animals). *P < 0,05 compared to corresponding control (Student’s t-test).