Antidepressant-like effects of the aqueous macerate of the bulb of Gladiolus dalenii Van Geel (Iridaceae) in a rat model of epilepsy-associated depression

Table 1 Effect of G.dalenii on the locomotor activity assessed on the open field test

Treatments	Doses (mg/kg)	Crossing	Rearing	Time spent in the center (s)
Saline	-	30.8 ± 7.86	3.4 ± 1.06	5.6 ± 0.93
GD	15	11 ± 2.33 **	1 ± 0.66 *	6.2 ± 0.86
Fluoxetine	15	33.2 ± 4.46	2.8 ± 0.53	5.2 ± 1.2

Saline, G. dalenii, and fluoxetine were administrated every day for seven days. Rats were treated with saline, G. dalenii and fluoxetine every day for seven days. The value represent means ± SEM (n = 5 rats per group). *p < 0.05; **p < 0.01 compare to the control group (one way ANOVA followed by Newmann Keuls test).
GD: G. dalenii: aqueous macerate of the bulb of Gladiolus dalenii.

ISSN: 2662-7671