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Table 2 Blood glucose level of type 1 diabetic mice and type 2 diabetic rats of treating with polysaccharides

From: Hypoglycemic effect of polysaccharides with different molecular weight of Pseudostellaria heterophylla

Groups

Doses

T1DM mice blood glucose levels(mmol/L)

Relative to model control (30thday)

T2DM rats blood glucose levels(mmol/L)

Relative to model control 30thday

  

Day 0

Day 15

Day 30

 

Day 0

Day 15

Day 30

 

Normal control

 

7.7 ± 1.2

6.7 ± 1.6

5.4 ± 2.3

 

5.7 ± 2.1

5.60 ± 0.28**

3.91 ± 1.38**

 

Model control

 

52.1 ± 7.6

51.3 ± 10.4

42.6 ± 2.8

 

23.9 ± 6.6

19.77 ± 3.69

25.10 ± 0.61

 

Positive control

 

62.5 ± 9.8

24.4 ± 4.9

10.4 ± 6.0**

↓75.58%

23.5 ± 4.8

14.04 ± 2.55**

6.72 ± 1.57**

↓73.22%

PH-TP

H

54.6 ± 3.1

52.2 ± 1.6

37.9 ± 5.5*

↓11.03%

25.0 ± 2.4

18.69 ± 4.22c

14.84 ± 2.41**

↓40.87%

 

M

56.0 ± 2.4

51.8 ± 6.8

48.8 ± 7.1C

↑14.55%

24.2 ± 2.5

16.73 ± 2.95c

16.67 ± 2.41**

↓33.59%

 

L

56.8 ± 2.8

50.1 ± 5.2

40.1 ± 5.3C

↓5.87%

23.4 ± 5.8

16.68 ± 2.69c

12.95 ± 0.92**

↓48.41%

PF40

H

52.9 ± 5.5

50.8 ± 4.3

37.5 ± 8.7*

↓11.97%

24.0 ± 5.7

15.78 ± 5.05*

6.78 ± 5.47**

↓72.99%

 

M

51.2 ± 4.1

49.4 ± 3.5

34.2 ± 8.0*

↓19.72%

25.2 ± 3.1

15.82 ± 3.67*

11.41 ± 2.89**

↓54.54%

 

L

50.2 ± 6.3

47.6 ± 7.1

40.4 ± 7.3C

↓5.16%

23.3 ± 6.9

15.25 ± 1.95*

12.80 ± 1.15**

↓49.00%

PF60

H

52.8 ± 6.6

49.9 ± 2.7

37.4 ± 11.3*

↓12.21%

24.0 ± 4.4

19.82 ± 6.98c

13.73 ± 5.24**

↓45.30%

 

M

54.9 ± 6.5

47.2 ± 4.1

40.1 ± 4.1C

↓5.87%

23.7 ± 5.1

16.05 ± 2.85*

14.98 ± 6.05**

↓40.32%

 

L

51.7 ± 1.1

45.3 ± 5.9

41.5 ± 3.6C

↓2.58%

24.7 ± 1.1

12.99 ± 3.66*

12.82 ± 4.97**

↓48.92%

PF90

H

50.7 ± 1.3

50.5 ± 4.8

40.2 ± 14.3C

↓5.63%

23.9 ± 1.3

16.31 ± 2.24*

14.77 ± 3.73**

↓41.16%

 

M

56.3 ± 2.0

52.4 ± 5.7

39.5 ± 5.0 C

↓7.27%

25.3 ± 2.0

15.13 ± 2.53*

14.83 ± 2.29**

↓40.92%

 

L

52.2 ± 0.99

47.6 ± 7.5

39.8 ± 5.2C

↓6.57%

22.2 ± 0.99

16.74 ± 2.33c

17.08 ± 3.56**

↓31.95%

  1. Values are expressed as mean ± S.d., n = 10.
  2. Significantly different from the model group at* P ≤ 0.05, ** P ≤ 0.01.
  3. Cversus model is NOT different.
  4. The sign “↓” expresses fall and “↑” expresses rise.